Programmed cell death proteins and chronic leukemia
نویسندگان
چکیده
منابع مشابه
Mitochondrial fission proteins regulate programmed cell death in yeast.
The possibility that single-cell organisms undergo programmed cell death has been questioned in part because they lack several key components of the mammalian cell death machinery. However, yeast encode a homolog of human Drp1, a mitochondrial fission protein that was shown previously to promote mammalian cell death and the excessive mitochondrial fragmentation characteristic of apoptotic mamma...
متن کاملApoptosis: programmed cell death.
C urrently there is much interest and excitement in the understanding of how cells undergo the process of apoptosis or programmed cell death. Understanding how, why, and when cells are instructed to die may provide insight into the aging process, autoimmune syndromes, degenerative diseases, and malignant transformation. This review focuses on the development of apoptosis and describes the proce...
متن کاملProgrammed cell death.
Programmed cell death is an integral component of C. elegans development. Genetic studies in C. elegans have led to the identification of more than two dozen genes that are important for the specification of which cells should live or die, the activation of the suicide program, and the dismantling and removal of dying cells. Molecular and biochemical studies have revealed the underlying conserv...
متن کاملProgrammed cell death *
Programmed cell death is an integral component of C. elegans development. Genetic studies in C. elegans have led to the identification of more than two dozen genes that are important for the specification of which cells should live or die, the activation of the suicide program, and the dismantling and removal of dying cells. Molecular and biochemical studies have revealed the underlying conserv...
متن کامل[Apoptosis--programmed cell death].
Apoptosis is a highly organized physiologic mechanism of destroying injured and abnormal cells as well as maintaining homeostasis in the multicellular organism. Apoptosis is tightly controlled at the genetic level and dysregulation of the apoptosis machinery may contribute to a variety of diseases. Pharmacologic manipulation of this pathway is a novel therapeutic target.
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ژورنال
عنوان ژورنال: Arhiv za bioloske nauke
سال: 2011
ISSN: 0354-4664,1821-4339
DOI: 10.2298/abs1103527b